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Thursday, April 2, 2020

IISc Bengaluru developing ventilator to save coronavirus patients

coronavirus
"A team of scientists and engineers are building a prototype of an electro-mechanical ventilator using local components," the institute said.
Twitter / @iiscbangalore
The Indian Institute of Science (IISc) is racing against time to develop a home-grown ventilator to save lives of COVID-19 (coronavirus) patients across the country, a statement said on Wednesday. "A team of scientists and engineers are building a prototype of an electro-mechanical ventilator using local components," said the over-century-old institute in the statement. Even as hundreds of patients grapple with the Covid-19 pandemic across the country and hospitals set to face shortage of the life-saving instrument, the team has designed the prototype based on guidelines of the British medicine and healthcare products regulatory agency. "As local manufacturers are unbale to source key components like sensors and flow controllers from overseas due to disruption in global supply chain, we are using only local parts made in India," said the institute's principal research scientist T.V. Prabhakar. The project is undertaken by the department of electronic systems engineering at the institute. "We are assembling the ventilator for use free of cost. The prototype will be ready for trials in the next couple of weeks. We hope by this month-end, manufacturers can make them and scalp up soon," said associate professor and project coordinator Gaurab Banerjee. Though about 40,000 ventilators are available across the country, they will be required in thousands if the virus cases spike rapidly. "Patients with severe Covid infection have damaged lungs that gasp for oxygen. When they are put on a ventilator, the machine enables lung function, feeding them with air and oxygen to fight the virus," said Prabhakar. A well-designed ventilator will have sensors and actuators that allow doctors to set the volume and pressure of gas delivered to the patient precisely, which depends on the severity of their illness. To store and mix air and oxygen, for instance, some component makers reused sedimentation tanks found in household RO water purifiers. "Our mixing process has parallels to those in gas turbines and industrial burners, where the ratio of fuel and oxidizer is carefully controlled," Aerospace engineering department's assistant professor Pratisha Panda said. To check pressure levels, sensors similar to those are used to detect air pressure in car tyres. "Controlling the pressure at which gas is pumped into the patient's lungs is crucial, akin to how using an industrial pressurised hose to water plants instead of a garden hose can cause severe damage," the faculty members warned the doctors. The team is also developing a flow rate sensor, which shows how much air is flowing into a patient's lungs. "By using concepts of fluid and gas dynamics, we are able to estimate and control pressure, volume and oxygen concentration of the air delivered to the patient," said team member Duvvuri Subrahamanyam. The team is taking inputs from doctors to simplify the interface and build a dashboard preloaded with approved settings. The dashboard will allow it to operate in an emergency by technicians or nurses. "They will have to press a button that says pneumonia or Acute Respiratory Distress Syndrome (ARDS) and all the settings will come up by default within a certain range," said Banerjee. "We are working with manufacturers to check components required for including them in the final design," said team member Manish Arora. State-run organisations like Bharat Heavy Electricals Ltd (BHEL) have expressed interest in supporting mass production. "The institute's centre for nano science and engineering has provided the team with local oxygen and pressure sensors," Arora added.
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The mysterious Mysuru cluster: 16 people with COVID-19, but no sign of a source yet

Coronavirus
So far, in Karnataka, this is the biggest known cluster of COVID-19 cases and the Mysuru district administration is yet to pinpoint the source of the infection.
Four more people tested positive for coronavirus in Mysuru district of Karnataka on Wednesday taking the tally of people affected by one pharmaceutical employee to 16.  So far, in Karnataka, this is the biggest known cluster of COVID-19 cases and the Mysuru district administration is yet to pinpoint the source of the infection. None of the patients have any foreign travel history or had any contact with any other patient. Mysuru Deputy Commissioner Abhiram G Shankar told TNM that health authorities in the district are examining three different ways the virus could have infected the first case (patient 52), a 35-year-old man who works in the quality assurance section of Jubilant Life Sciences, a company based in Nanjangud in the district.  He tested positive on March 26 and since then, 16 people who came in contact with him have tested positive including his wife and colleagues. Patient 52 did not have any known foreign travel or contact history.  “We are cross checking if the information given by patient 52 about his movements is true. We are checking the visitor log of the pharmaceutical company for foreign nationals who had visited.We are also checking consignments the company had received from abroad,” Mysuru DC Abhiram G Shankar told TNM. The samples of the consignments were sent to the National Institute of Virology in Pune for testing, Jawaid Akhtar, Additional Chief Secretary, Health, Karnataka Health and Family Welfare Department. Confirmed. The company had imported a gel from China, officiais stated.  Stringent lockdown measures were imposed in Nanjangud when the first set of cases were reported. All activity in the town has been suspended with only one entry and exit point open for the movement of essential goods and emergency services.  Around 1,400 employees of the pharmaceutical company are also currently quarantined in their homes.  A 3 km buffer zone has been created in Nanjangud town and Accredited Social Health Activist (ASHA) workers are going door-to-door to collect information about anyone reporting symptoms.  Health authorities are waiting for information from the National Institute of Virology in Pune about the parcels sent for testing. They are also searching for who they believe could be patient zero i.e a person with foreign travel history who infected patient 52.  A total of 110 cases of coronavirus were reported in Karnataka as of Wednesday night. Apart from the cluster in Mysuru, smaller clusters of cases were reported in Uttara Kannada and Chikkaballapura districts of the state.     
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Fauci gets security detail after receiving threats

HHS Secretary Alex Azar had grown concerned about the growing online attacks against Fauci — whose profile soared since he started regularly flanking Trump at White House coronavirus briefings.

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FEMA braces for a multi-front war as hurricane season looms

“Covid is the equivalent of Hurricane Katrina hitting 50 states,” said one former FEMA official.

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Trump hints at using federal programs to provide coverage after Obamacare decision

The president and vice president offered vague assurances after Democrats ripped Trump's refusal to reopen Obamacare enrollment.

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Chinese county goes into coronavirus lockdown amid fear of second wave

Authorities order residents of Jia county to stay home after reports of cases linked to the area’s hospital.

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Wednesday, April 1, 2020

'Walk to grocery shops, do not go everyday', Bengaluru Police Commissioner

Coronavirus
Over 6800 seized vehicles will be released only after 14 April, Bengaluru Police Commissioner Bhaskar Rao said.
Bengaluru Police Commissioner Bhaskar Rao reiterated that two-wheeler and four-wheeler vehicles that ply on the city's roads will be seized during the lockdown period imposed following the outbreak of coronavirus in the country. "I am telling citizens to walk to grocery stores or limit your needs. There is no need for(them) to roam around in vehicles," Bhaskar Rao said on Wednesday after an announcement was made about restrictions on the use of vehicles even to buy grocery.  "This is not the time to do grocery shopping. We have given enough time for you to use vehicles and go to shops and buy. Do not go everyday to your shop for groceries. I have commanded the police under my control to impound two- wheelers and four-wheelers moving around aimlessly and which are proving to be a hindrance in enforcing lockdown," Bhaskar Rao added.     According to the Commissioner, 6852 vehicles were seized in Bengaluru until Wednesday night. This includes 6321 two-wheelers, 227 three-wheelers and 304 four-wheelers. The vehicles will be released only after 14 April.  "We are planning to issue 200 medical emergency passes per police station which can be collected and returned on a daily basis," added Bhaskar Rao. Earlier in the day, Praveen Sood, Director General & inspector general of police of Karnataka, posted on Twitter that the state police will stop vehicles found roaming outside for flimsy reasons.   "This is not an April Fool's prank. Two/ four wheelers are banned from use till the 14th of April. We will SEIZE your vehicle if you CEASE to ignore this lockdown regulation," said a tweet by the DGP. This is not an April Fool's prank. Two/ four wheelers are banned from use till the 14th of April. We will SEIZE your vehicle if you CEASE to ignore this lockdown regulation. — DGP KARNATAKA (@DgpKarnataka) April 1, 2020 In Bengaluru, groceries are allowed to be open through out the day but police officials are restricting people from using their vehicles. However, vehicles will be allowed to ply for emergencies.   
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